Commonly used as a solvent in chemical syntheses. THF has a low boiling point, making it useful for synthesizing low-melting-point compounds, and it has a high solubility for a wide range of organic compounds. It is also a good solvent for many organic compounds, including alkali metals, making it useful in the synthesis of organometallic compounds. THF is highly reactive and can undergo various reactions, including nucleophilic substitution, electrophilic addition and polymerization. Because of its reactivity and low toxicity, THF is a useful starting material for a wide range of syntheses.